The National League and the American Association faced each other in a World's Championship Series at the end of the season to determine an overall champion.
Champ
NYG
1888 NL Champion New York Giants
z: best record, c: conference winner, y: division winner, w: wildcard, x: clinched playoff spot

World's Championship Series

Best of 11-game series
Home/Away matchups are not known
Date    OpponentResultScoreSeries
10/16vs StL BrownsW  2-1 1-0
10/17vs StL BrownsL  0-3 1-1
10/18vs StL BrownsW  4-2 2-1
10/19at StL BrownsW  6-3 3-1
10/20vs StL BrownsW  6-4
8
4-1
10/22at StL BrownsW  12-5
8
5-1
10/24at StL BrownsL  5-7
8
5-2
10/25at StL BrownsW  11-3 6-2
10/26at StL BrownsL  11-14
10
6-3
10/27at StL BrownsL  7-18 6-4