The season was extended one week, each team playing 17 games with one bye-week across the 18-week schedule.

2021 Regular Season Results

Date    OpponentResultScoreRecord
9/12at CarolinaL  14-19 0-1
9/19vs New EnglandL  6-25 0-2
9/26at DenverL  0-26 0-3
10/3vs TennesseeW  27-24
OT
1-3
10/10at AtlantaL  20-27 1-4
10/24at New EnglandL  13-54 1-5
10/31vs CincinnatiW  34-31 2-5
11/4at IndianapolisL  30-45 2-6
11/14vs BuffaloL  17-45 2-7
11/21vs MiamiL  17-24 2-8
11/28at HoustonW  21-14 3-8
12/5vs PhiladelphiaL  18-33 3-9
12/12vs New OrleansL  9-30 3-10
12/19at MiamiL  24-31 3-11
12/26vs JacksonvilleW  26-21 4-11
1/2vs Tampa BayL  24-28 4-12
1/9at BuffaloL  10-27 4-13