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Astros All-Time Leaders
Strikeouts

1
Profile photo of Nolan Ryan

Nolan Ryan

1980-1988

1,866

2
Profile photo of Roy Oswalt

Roy Oswalt

2001-2010

1,593

3
Profile photo of J. R. Richard

J. R. Richard

1971-1980

1,493

4
Profile photo of Larry Dierker

Larry Dierker

1964-1976

1,487

5
Profile photo of Mike Scott

Mike Scott

1983-1991

1,318

6
Profile photo of Shane Reynolds

Shane Reynolds

1992-2002

1,309

7
Profile photo of Don Wilson

Don Wilson

1966-1974

1,283

8
Profile photo of Joe Niekro

Joe Niekro

1975-1985

1,178

9
Profile photo of Wandy Rodriguez

Wandy Rodriguez

2005-2012

1,093

10
Profile photo of Darryl Kile

Darryl Kile

1991-1997

973

11
Profile photo of Bob Knepper

Bob Knepper

1981-1989

946

12
Profile photo of Dallas Keuchel

Dallas Keuchel

2012-2018

945

13
Profile photo of Ken Forsch

Ken Forsch

1970-1980

815

14
Profile photo of Mike Hampton

Mike Hampton

1994-2009

767

15
Profile photo of Lance McCullers

Lance McCullers

2015-2021

750

16
Profile photo of Collin McHugh

Collin McHugh

2014-2019

743

17
Profile photo of Jim Deshaies

Jim Deshaies

1985-1991

731

18
Profile photo of Dick 'Turk' Farrell

694

19
Profile photo of Billy Wagner

Billy Wagner

1995-2003

694

20
Profile photo of Wade Miller

Wade Miller

1999-2004

659

21
Profile photo of Tom Griffin

Tom Griffin

1969-1976

652

22
Profile photo of Bud Norris

Bud Norris

2009-2013

643

23
Profile photo of Justin Verlander

Justin Verlander

2017-2020

640

24
Profile photo of Dave Giusti

Dave Giusti

1962-1968

625

25
Profile photo of Bob Bruce

Bob Bruce

1962-1966

609

26
Profile photo of Gerrit Cole

Gerrit Cole

2018-2019

602

27
Profile photo of Jose Lima

Jose Lima

1997-2001

584

28
Profile photo of Pete Harnisch

Pete Harnisch

1991-1994

583

29
Profile photo of Brad Peacock

Brad Peacock

2013-2020

583

30
Profile photo of Brad Lidge

Brad Lidge

2002-2007

561

31
Profile photo of Doug Drabek

Doug Drabek

1993-1996

558

32
Profile photo of Mike Cuellar

Mike Cuellar

1965-1968

557

33
Profile photo of Octavio Dotel

Octavio Dotel

2000-2004

552

34
Profile photo of Danny Darwin

Danny Darwin

1986-1996

543

35
Profile photo of Mark Portugal

Mark Portugal

1989-1993

535

36
Profile photo of Dave Smith

Dave Smith

1980-1990

529

37
Profile photo of Roger Clemens

Roger Clemens

2004-2006

505

38
Profile photo of Ken Johnson

Ken Johnson

1962-1965

471

39
Profile photo of Denny Lemaster

Denny Lemaster

1968-1971

450

40
Profile photo of Andy Pettitte

Andy Pettitte

2004-2006

428

41
Profile photo of Joe Sambito

Joe Sambito

1976-1984

421

42
Profile photo of Dave Roberts

Dave Roberts

1972-1975

403

43
Profile photo of Joaquin Andujar

Joaquin Andujar

1976-1988

388

44
Profile photo of Scott Elarton

Scott Elarton

1998-2001

384

45
Profile photo of Jim Ray

Jim Ray

1965-1973

381

46
Profile photo of Charlie Morton

Charlie Morton

2017-2018

364

47
Profile photo of Brett Myers

Brett Myers

2010-2012

360

48
Profile photo of Xavier Hernandez

Xavier Hernandez

1990-1996

354

49
Profile photo of Jerry Reuss

Jerry Reuss

1972-1973

351

50
Profile photo of Chris Holt

Chris Holt

1996-2000

346

51
Profile photo of Larry Andersen

Larry Andersen

1986-1990

346

52
Profile photo of Jack Billingham

Jack Billingham

1969-1971

344

53
Profile photo of Mike Fiers

Mike Fiers

2015-2017

339

54
Profile photo of Chris Devenski

Chris Devenski

2016-2020

332

55
Profile photo of Brandon Backe

Brandon Backe

2004-2009

318

56
Profile photo of Will Harris

Will Harris

2015-2019

315

57
Profile photo of Vern Ruhle

Vern Ruhle

1978-1984

313

58
Profile photo of Greg Swindell

Greg Swindell

1993-1996

309

59
Profile photo of Chad Qualls

Chad Qualls

2004-2015

307

60
Profile photo of Framber Valdez

Framber Valdez

2018-2021

303

61
Profile photo of J. A. Happ

J. A. Happ

2010-2012

293

62
Profile photo of Tim Redding

Tim Redding

2001-2004

290

63
Profile photo of Don Nottebart

Don Nottebart

1963-1965

285

64
Profile photo of Jordan Lyles

Jordan Lyles

2011-2013

259

65
Profile photo of Wade Blasingame

Wade Blasingame

1967-1972

258

66
Profile photo of Hal Woodeshick

Hal Woodeshick

1962-1965

256

67
Profile photo of Lucas Harrell

Lucas Harrell

2011-2014

248

68
Profile photo of Tony Sipp

Tony Sipp

2014-2018

246

69
Profile photo of Don Sutton

Don Sutton

1981-1982

243

70
Profile photo of Brian Moehler

Brian Moehler

2003-2010

242

71
Profile photo of Zack Greinke

Zack Greinke

2019-2021

239

72
Profile photo of Wesley Wright

Wesley Wright

2008-2013

238

73
Profile photo of Frank DiPino

Frank DiPino

1982-1986

233

74
Profile photo of Frank LaCorte

Frank LaCorte

1979-1983

229

75
Profile photo of Todd Jones

Todd Jones

1993-1996

228

76
Profile photo of Claude Raymond

Claude Raymond

1964-1967

225

77
Profile photo of Brian Williams

Brian Williams

1991-1999

216

78
Profile photo of Ken Giles

Ken Giles

2016-2018

216

79
Profile photo of Ryan Pressly

Ryan Pressly

2018-2021

214

80
Profile photo of Scott Feldman

Scott Feldman

2014-2016

210

81
Profile photo of Floyd Bannister

Floyd Bannister

1977-1978

206

82
Profile photo of Dan Wheeler

Dan Wheeler

2004-2007

202

83
Profile photo of Josh Fields

Josh Fields

2013-2016

197

84
Profile photo of Luke Gregerson

Luke Gregerson

2015-2017

196

85
Profile photo of Mike LaCoss

Mike LaCoss

1982-1984

190

86
Profile photo of Felipe Paulino

Felipe Paulino

2007-2010

187

87
Profile photo of Cristian Javier

Cristian Javier

2020-2021

184

88
Profile photo of Russ Springer

Russ Springer

1997-2006

183

89
Profile photo of Jim Owens

Jim Owens

1964-1967

179

90
Profile photo of Chris Sampson

Chris Sampson

2006-2010

176

91
Profile photo of Luis Garcia

Luis Garcia

2020-2021

176

92
Profile photo of Michael Feliz

Michael Feliz

2015-2017

172

93
Profile photo of George Culver

George Culver

1970-1972

170

94
Profile photo of Trever Miller

Trever Miller

1998-2007

169

95
Profile photo of Wilton Lopez

Wilton Lopez

2009-2012

169

96
Profile photo of Mark Lemongello

Mark Lemongello

1976-1978

169

97
Profile photo of Jim Clancy

Jim Clancy

1989-1991

168

98
Profile photo of Brett Oberholtzer

Brett Oberholtzer

2013-2015

166

99
Profile photo of Jay Powell

Jay Powell

1998-2001

159

100
Profile photo of Doug Jones

Doug Jones

1992-1993

159