Due to a mid-season players' strike, the season was divided into a first half and a second half. The division winner of each half played each other in a five-game divisional series. The Cincinnati Reds, despite having the best overall record during the season, finished 2nd in both halves, so did not qualify for the post-season.

1981 Regular Season Results

Date    OpponentResultScoreRecord
4/9vs TorontoW  6-2 1-0
4/11vs TorontoW  6-2 2-0
4/12vs TorontoL  2-6 2-1
4/14at Kansas CityW  6-5 3-1
4/15at Kansas CityW  4-0 4-1
4/16at TorontoW  2-0 5-1
4/17at TorontoW  8-5 6-1
4/18at TorontoW  4-3 7-1
4/19at TorontoL  1-9 7-2
4/20at NY YankeesL  2-6 7-3
4/21at NY YankeesL  0-2 7-4
4/22at NY YankeesL  2-7 7-5
4/24vs Chi. White SoxL  2-3
10
7-6
4/25vs Chi. White SoxL  0-4 7-7
4/26vs Chi. White SoxL  4-5 7-8
4/27vs NY YankeesL  1-3 7-9
4/28vs NY YankeesL  1-4 7-10
4/29vs NY YankeesL  2-3 7-11
4/30at SeattleW  2-0 8-11
5/1at SeattleW  7-3 9-11
5/2at SeattleL  1-3 9-12
5/3at SeattleW  8-5 10-12
5/5at OaklandL  2-6 10-13
5/6at OaklandW  3-2 11-13
5/7at OaklandL  3-5 11-14
5/8at CaliforniaW  6-1 12-14
5/9at CaliforniaL  1-15 12-15
5/10at CaliforniaL  3-4 12-16
5/12vs SeattleW  6-2 13-16
5/13vs SeattleW  1-0 14-16
5/15vs CaliforniaW  5-1 15-16
5/16vs CaliforniaW  7-5 16-16
5/17vs CaliforniaL  1-7 16-17
5/18vs TexasL  5-13 16-18
5/19vs TexasW  14-1 17-18
5/20vs TexasW  8-4 18-18
5/22vs BaltimoreL  2-4 18-19
5/23vs BaltimoreL  2-9 18-20
5/24vs BaltimoreW  5-3 19-20
5/24vs BaltimoreW  8-2 20-20
5/25at MilwaukeeW  12-3 21-20
5/26at MilwaukeeL  3-7 21-21
5/27at MilwaukeeL  1-5 21-22
5/28at MilwaukeeL  1-7 21-23
5/29at BaltimoreL  5-6 21-24
5/30at BaltimoreW  4-1 22-24
5/31at BaltimoreW  5-4 23-24
6/1vs MilwaukeeW  4-3
12
24-24
6/2vs MilwaukeeL  2-5 24-25
6/3vs MilwaukeeW  4-1 25-25
6/5vs MinnesotaW  2-0 26-25
6/6vs MinnesotaW  5-1 27-25
6/7vs MinnesotaW  3-0 28-25
6/8at TexasL  1-8 28-26
6/9at TexasW  5-0 29-26
6/10at MinnesotaW  4-2 30-26
6/11at MinnesotaW  7-2 31-26
8/10vs TorontoW  4-3 32-26
8/11vs TorontoL  4-6 32-27
8/12vs TorontoL  3-4 32-28
8/13vs NY YankeesL  0-3 32-29
8/14vs NY YankeesW  1-0 33-29
8/15vs NY YankeesW  8-5 34-29
8/16vs NY YankeesW  5-4 35-29
8/17vs MinnesotaW  12-2 36-29
8/18vs MinnesotaW  3-0 37-29
8/19vs MinnesotaW  4-0 38-29
8/21vs TexasW  7-4 39-29
8/22vs TexasW  2-0 40-29
8/23vs TexasW  5-4 41-29
8/24vs Kansas CityL  2-4 41-30
8/25vs Kansas CityW  4-3
10
42-30
8/26vs Kansas CityL  1-6 42-31
8/27at MinnesotaL  3-4 42-32
8/28at MinnesotaL  0-6 42-33
8/29at MinnesotaL  1-7 42-34
8/30at MinnesotaW  6-1 43-34
8/31at Chi. White SoxW  3-1 44-34
9/1at Chi. White SoxW  2-1 45-34
9/2at Chi. White SoxW  5-4
10
46-34
9/3at TexasW  8-5 47-34
9/4at TexasL  2-3 47-35
9/5at TexasW  1-0 48-35
9/6at TexasW  4-3 49-35
9/7vs BostonW  3-1 50-35
9/8vs BostonL  3-5 50-36
9/9vs BostonL  5-6
11
50-37
9/11vs ClevelandW  6-3 51-37
9/12vs ClevelandW  11-9
12
52-37
9/13vs ClevelandW  8-6 53-37
9/14at BostonL  2-5 53-38
9/16at BostonL  1-2
10
53-39
9/16at BostonL  4-5 53-40
9/17at BostonL  1-6 53-41
9/18at ClevelandL  4-8 53-42
9/19at ClevelandW  4-3 54-42
9/20at ClevelandW  5-1 55-42
9/21at BaltimoreW  5-1 56-42
9/22at BaltimoreW  6-3 57-42
9/23at BaltimoreL  0-1 57-43
9/25vs MilwaukeeL  6-8 57-44
9/26vs MilwaukeeL  3-4 57-45
9/27vs MilwaukeeW  2-1 58-45
9/28vs BaltimoreL  3-7 58-46
9/29vs BaltimoreW  14-0 59-46
10/1vs BaltimoreL  4-5
10
59-47
10/2at MilwaukeeL  2-8 59-48
10/3at MilwaukeeL  1-2 59-49
10/4at MilwaukeeW  3-2 60-49