The temporary rule changes for the 2020 season would continue in the 2021 regular season: A runner will be placed on second base at the start of every half-inning of any game that goes into extra innings. Doubleheaders will be played as two seven-inning games.

2021 Regular Season Results

Date    OpponentResultScoreRecord
4/1at DetroitL  2-3 0-1
4/3at DetroitL  2-5 0-2
4/4at DetroitW  9-3 1-2
4/5vs Kansas CityL  0-3 1-3
4/7vs Kansas CityW  4-2 2-3
4/9vs DetroitW  4-1 3-3
4/10vs DetroitW  11-3 4-3
4/11vs DetroitW  5-2 5-3
4/12at Chi. White SoxL  3-4 5-4
4/13at Chi. White SoxW  2-0
10		 6-4
4/14at Chi. White SoxL  0-8 6-5
4/15at Chi. White SoxW  4-2 7-5
4/16at CincinnatiL  3-10 7-6
4/17at CincinnatiL  2-3
10		 7-7
4/18at CincinnatiW  6-3 8-7
4/20vs Chi. White SoxL  5-8 8-8
4/22vs NY YankeesL  3-6 8-9
4/23vs NY YankeesL  3-5 8-10
4/24vs NY YankeesL  1-2 8-11
4/25vs NY YankeesW  7-3 9-11
4/26vs MinnesotaW  5-3
10		 10-11
4/27vs MinnesotaW  7-4 11-11
4/28vs MinnesotaL  2-10 11-12
4/30at Chi. White SoxW  5-3 12-12
5/1at Chi. White SoxL  3-7 12-13
5/2at Chi. White SoxW  5-0 13-13
5/3at Kansas CityW  8-6 14-13
5/4at Kansas CityW  7-3 15-13
5/5at Kansas CityW  5-4 16-13
5/6at Kansas CityW  4-0 17-13
5/7vs CincinnatiL  0-3 17-14
5/8vs CincinnatiW  9-2 18-14
5/11vs Chi. CubsW  3-2 19-14
5/12vs Chi. CubsW  2-1
10		 20-14
5/13at SeattleW  4-2 21-14
5/14at SeattleL  3-7 21-15
5/15at SeattleL  3-7 21-16
5/16at SeattleL  2-3 21-17
5/17at LA AngelsL  4-7 21-18
5/18at LA AngelsW  6-5 22-18
5/19at LA AngelsW  3-2 23-18
5/21vs MinnesotaL  0-10 23-19
5/22vs MinnesotaW  5-3
10		 24-19
5/23vs MinnesotaL  5-8
10		 24-20
5/24at DetroitW  6-5 25-20
5/25at DetroitW  4-1 26-20
5/26at DetroitL  0-1 26-21
5/27at DetroitW  5-2 27-21
5/28vs TorontoL  2-11
7		 27-22
5/30vs TorontoL  1-4
7		 27-23
5/30vs TorontoW  6-5
7		 28-23
5/31vs Chi. White SoxL  6-8
8		 28-24
5/31vs Chi. White SoxW  3-1
7		 29-24
6/1vs Chi. White SoxW  6-5 30-24
6/4at BaltimoreL  1-3 30-25
6/5at BaltimoreW  10-4 31-25
6/6at BaltimoreL  5-18 31-26
6/8at StL CardinalsW  10-1 32-26
6/9at StL CardinalsL  2-8 32-27
6/11vs SeattleW  7-0 33-27
6/12vs SeattleW  5-4
10		 34-27
6/13vs SeattleL  2-6 34-28
6/14vs BaltimoreW  4-3 35-28
6/15vs BaltimoreW  7-2 36-28
6/16vs BaltimoreW  8-7 37-28
6/17vs BaltimoreW  10-3 38-28
6/18at PittsburghL  10-11 38-29
6/19at PittsburghL  3-6 38-30
6/20at PittsburghW  2-1 39-30
6/21at Chi. CubsW  4-0 40-30
6/22at Chi. CubsL  1-7 40-31
6/24at MinnesotaW  4-1 41-31
6/25at MinnesotaL  7-8 41-32
6/27at MinnesotaL  2-8 41-33
6/28vs DetroitW  13-5 42-33
6/30vs DetroitL  4-9
7		 42-34
6/30vs DetroitL  1-7
7		 42-35
7/1vs HoustonL  2-7 42-36
7/2vs HoustonL  3-6 42-37
7/3vs HoustonL  2-3 42-38
7/4vs HoustonL  3-4
10		 42-39
7/5at Tampa BayL  8-9 42-40
7/7at Tampa BayL  1-8
7		 42-41
7/7at Tampa BayL  0-4
7		 42-42
7/8vs Kansas CityW  7-4 43-42
7/9vs Kansas CityW  2-1 44-42
7/10vs Kansas CityW  14-6 45-42
7/16at OaklandL  4-5 45-43
7/17at OaklandW  3-2 46-43
7/18at OaklandW  4-2 47-43
7/19at HoustonL  3-4 47-44
7/20at HoustonL  3-9 47-45
7/21at HoustonW  5-4 48-45
7/22vs Tampa BayL  4-5
10		 48-46
7/23vs Tampa BayL  5-10 48-47
7/24vs Tampa BayL  2-8 48-48
7/25vs Tampa BayW  3-2 49-48
7/27vs StL CardinalsL  2-4 49-49
7/28vs StL CardinalsW  7-2 50-49
7/30at Chi. White SoxL  4-6 50-50
7/31at Chi. White SoxW  12-11 51-50
8/1at Chi. White SoxL  1-2 51-51
8/2at TorontoW  5-2
10		 52-51
8/3at TorontoL  2-7 52-52
8/4at TorontoL  6-8 52-53
8/5at TorontoL  0-3 52-54
8/6vs DetroitW  6-1 53-54
8/7vs DetroitL  1-2 53-55
8/8vs DetroitW  7-5 54-55
8/9vs CincinnatiW  9-3 55-55
8/10vs OaklandL  3-4
10		 55-56
8/11vs OaklandL  3-6 55-57
8/12vs OaklandL  0-17 55-58
8/13at DetroitW  7-4 56-58
8/14at DetroitL  4-6 56-59
8/15at DetroitW  11-0 57-59
8/16at MinnesotaL  4-5
10		 57-60
8/17at MinnesotaW  3-1 58-60
8/18at MinnesotaL  7-8
11		 58-61
8/20vs LA AngelsW  9-1 59-61
8/21vs LA AngelsW  5-1 60-61
8/22vs LA AngelsW  3-0 61-61
8/24vs TexasL  3-7 61-62
8/25vs TexasW  7-2 62-62
8/26vs TexasW  10-6 63-62
8/27vs BostonL  3-4 63-63
8/28vs BostonL  3-5
10		 63-64
8/29vs BostonW  7-5 64-64
8/31at Kansas CityW  7-2 65-64
9/1at Kansas CityW  5-3
11		 66-64
9/2at Kansas CityW  4-2 67-64
9/3at BostonL  5-8 67-65
9/4at BostonL  3-4 67-66
9/5at BostonW  11-5 68-66
9/6vs MinnesotaL  2-5 68-67
9/7vs MinnesotaL  0-3 68-68
9/8vs MinnesotaL  0-3 68-69
9/9vs MinnesotaW  4-1 69-69
9/10vs MilwaukeeL  3-10 69-70
9/11vs MilwaukeeL  0-3 69-71
9/12vs MilwaukeeL  1-11 69-72
9/14at MinnesotaW  3-1
7		 70-72
9/14at MinnesotaL  3-6
7		 70-73
9/15at MinnesotaW  12-3 71-73
9/17at NY YankeesL  0-8 71-74
9/18at NY YankeesW  11-3 72-74
9/19at NY YankeesW  11-1 73-74
9/20vs Kansas CityL  2-7
7		 73-75
9/20vs Kansas CityL  2-4
7		 73-76
9/21vs Kansas CityW  4-1 74-76
9/23vs Chi. White SoxL  2-7
7		 74-77
9/23vs Chi. White SoxW  5-3
7		 75-77
9/24vs Chi. White SoxL  0-1 75-78
9/25vs Chi. White SoxW  6-0 76-78
9/26vs Chi. White SoxL  2-5 76-79
9/27vs Kansas CityW  8-3 77-79
9/28at Kansas CityL  4-6 77-80
9/29at Kansas CityL  5-10 77-81
9/30at Kansas CityW  6-1 78-81
10/1at TexasW  9-6 79-81
10/2at TexasL  2-7 79-82
10/3at TexasW  6-0 80-82

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