The league was known as the American Professional Football Association (APFA) during the 1920 and 1921 seasons
| TEAM | W | L | T | Pct | ||
 | Akron | 8 | 0 | 3 | .864 | |
 | Decatur | 10 | 1 | 2 | .846 | |
 | Buffalo | 9 | 1 | 1 | .864 | |
 | Chi. Cardinals | 6 | 2 | 2 | .700 | |
 | Rock Island | 6 | 2 | 2 | .700 | |
 | Dayton | 5 | 2 | 2 | .667 | |
 | Rochester | 6 | 3 | 2 | .636 | |
 | Canton | 7 | 4 | 2 | .615 | |
 | Detroit | 2 | 3 | 3 | .438 | |
 | Cleveland | 2 | 4 | 2 | .375 | |
 | Hammond | 2 | 5 | 0 | .286 | |
 | Chi. Tigers | 2 | 5 | 1 | .313 | |
 | Columbus | 2 | 6 | 2 | .300 | |
 | Muncie | 0 | 1 | 0 | .000 |