The season was extended one week, each team playing 17 games with one bye-week across the 18-week schedule.

2021 Regular Season Results

Date    OpponentResultScoreRecord
9/13at Las VegasL  27-33
OT
0-1
9/19vs Kansas CityW  36-35 1-1
9/26at DetroitW  19-17 2-1
10/3at DenverW  23-7 3-1
10/11vs IndianapolisW  31-25
OT
4-1
10/17vs LA ChargersW  34-6 5-1
10/24vs CincinnatiL  17-41 5-2
11/7vs MinnesotaW  34-31
OT
6-2
11/11at MiamiL  10-22 6-3
11/21at ChicagoW  16-13 7-3
11/28vs ClevelandW  16-10 8-3
12/5at PittsburghL  19-20 8-4
12/12at ClevelandL  22-24 8-5
12/19vs Green BayL  30-31 8-6
12/26at CincinnatiL  21-41 8-7
1/2vs LA RamsL  19-20 8-8
1/9vs PittsburghL  13-16
OT
8-9