The arena was the home of the Dallas Mavericks from 1980 to 2001 and the Dallas Stars from 1993 to 2001. Both teams moved to the new American Airlines Center in 2001. The Dallas Desperados arena football team used the arena for its 2003 season but ultimately returned to American Airlines Center.

The arena's last remaining full-time sports tenant was the MISL Dallas Sidekicks, but the club was inactive after the fall of 2004.

Reunion Arena also hosted the WCT Tennis Tournament in the 1980s, including Virginia Slims Invitational Tournament. Due to scheduling conflicts in 1984, the WCT Tennis Tournament forced the Dallas Mavericks to play Game 5 of their first ever playoff series at Moody Coliseum, against the Seattle SuperSonics. While Southern Methodist University competed in the Southwest Conference, Reunion Arena was known by University of Arkansas Razorbacks fans as Barnhill South, due to the big following by the Arkansas fans away from home; the Barnhill Arena was the home to all UA games until 1993. Reunion Arena hosted the Southwest Conference's basketball tournament in the 1980s and 1990s, as well as the 1986 NCAA Final Four.

Reunion was also a venue that was frequently used by World Class Championship Wrestling in the 1980s, in which the organization held its bi-monthly Star Wars events.

Reunion Arena also served as the venue for WWE's November 9, 2000 SmackDown show.

🏟️