Petco Park is named after the San Diego-based pet supplies retailer Petco, which paid for the naming rights until 2028. The ballpark is between Seventh and 10th avenues, south of J Street. The park opened in 2004, replacing Qualcomm Stadium, which the Padres shared with the San Diego Chargers (now the Los Angeles Chargers) of the National Football League (NFL).

The southern side of the stadium is bounded by San Diego Trolley light rail tracks along the north side of Harbor Drive, which serve the adjacent San Diego Convention Center. The portion of K Street between Seventh and 10th now is closed to automobiles and serves as a pedestrian promenade along the back of the left and center field outfield seating and also provides access to the Park at the Park behind center field. Two of the stadium's outfield entrance areas are located at K Street's intersections with Seventh and 10th avenues. The main entrance, behind home plate, is at the south end of Park Boulevard (at Imperial) and faces the San Diego Trolley station 12th & Imperial Transit Center. The ballpark is also located approximately 1 mile (1.6 km) away from Santa Fe Depot station, which is served by Amtrak and Coaster.

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