Wade LeBlanc, a left-handed pitcher, embarked on his Major League Baseball journey when he was drafted by the San Diego Padres in the second round of the 2006 MLB Draft. He made his MLB debut with the Padres on September 3, 2008, against the Los Angeles Dodgers. During his initial years with the Padres, LeBlanc showcased his skills as a starting pitcher, although he faced challenges in maintaining consistency.

In 2011, LeBlanc was traded to the Miami Marlins, where he continued to develop his craft. His tenure with the Marlins saw him transition between starting and relief roles, a pattern that would become familiar throughout his career. LeBlanc's adaptability allowed him to find opportunities with various teams, even as he faced the ups and downs typical of a journeyman pitcher.

The Houston Astros acquired LeBlanc in 2013, but his time there was brief. He soon found himself with the Los Angeles Angels, where he continued to oscillate between the bullpen and the starting rotation. His ability to fill multiple roles made him a valuable asset for teams looking for depth in their pitching staff.

LeBlanc's career took an international turn in 2015 when he signed with the Seibu Lions of Nippon Professional Baseball in Japan. This experience abroad provided him with a new perspective and honed his pitching skills further. Upon returning to the United States, he signed a minor league deal with the Toronto Blue Jays in 2016, eventually making his way back to the majors with the Seattle Mariners.

His stint with the Mariners proved to be one of the more stable periods of his career. In 2018, LeBlanc enjoyed a solid season, posting a 9-5 record with a 3.72 ERA over 32 appearances, including 27 starts. This performance earned him a contract extension, reflecting the Mariners' confidence in his abilities.

LeBlanc's journey continued as he joined the Baltimore Orioles in 2020. The shortened season due to the COVID-19 pandemic presented unique challenges, but he managed to contribute to the Orioles' pitching staff. In 2021, he signed with the St. Louis Cardinals, where he provided veteran leadership and experience to a young pitching rotation.

Throughout his career, Wade LeBlanc played for multiple teams, including the Padres, Marlins, Astros, Angels, Yankees, Mariners, Pirates, Orioles, and Cardinals.