Throughout his career, Patterson was known for his pitching skills, which helped him secure a place in the White Sox's rotation. In his first season, he posted a 20-15 win-loss record, demonstrating his ability to compete at a high level. His performance contributed to the White Sox's strong showing in the league, as they finished the season in third place.
Patterson continued to be a reliable pitcher for the White Sox over the next few years. In 1902, he recorded a 15-15 win-loss record, and in 1903, he improved to 20-14. His consistency on the mound was a valuable asset to the team, and he was often called upon to pitch in important games. Patterson's pitching style was characterized by his control and ability to keep hitters off balance, which made him a challenging opponent for batters of that era.
In 1904, Patterson's performance began to decline, as he finished the season with a 10-11 record. Despite this, he remained a part of the White Sox's pitching staff. The following year, in 1905, he saw limited action, appearing in only 11 games and posting a 4-4 record. His reduced playing time was indicative of the changes happening within the team and the league as a whole.
Patterson's final season in the major leagues came in 1907. During this year, he played in just two games, and his time as a professional baseball player came to an end. Over the course of his career, Patterson compiled a win-loss record of 81-72, with an earned run average (ERA) of 3.11. He pitched a total of 1,384 innings and struck out 541 batters.
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