Roberto Petagine's journey through professional baseball is a tale of perseverance and adaptability across multiple leagues and countries. Born in Venezuela, Petagine began his career in Major League Baseball (MLB) when he was signed by the Houston Astros. He made his MLB debut with the Astros in 1994, but his time with the team was brief. Over the next few years, he played for several MLB teams, including the San Diego Padres, New York Mets, Cincinnati Reds, and Boston Red Sox. Despite his evident talent, Petagine struggled to secure a permanent spot on any MLB roster.

In the late 1990s, Petagine sought opportunities beyond the MLB, leading him to Japan, where he found a new stage to showcase his skills. Joining Nippon Professional Baseball (NPB), he played for the Yakult Swallows and later the Yomiuri Giants. His tenure in Japan proved to be a turning point in his career. Petagine excelled in the NPB, becoming one of the league's most feared hitters. His powerful batting and keen eye at the plate earned him the Central League MVP award in 2001 while playing for the Swallows. During his time in Japan, he consistently posted impressive statistics, including high batting averages and home run totals, which solidified his reputation as a formidable player in the league.

After several successful seasons in Japan, Petagine returned to the United States, hoping to translate his overseas success into a stable MLB career. He signed with the Boston Red Sox in 2005, but once again, he found limited opportunities to play regularly. Despite this, he continued to demonstrate his abilities whenever given the chance, contributing to the team with his experience and skill.

Petagine's career also included a stint in the Korean Baseball Organization (KBO), where he played for the LG Twins. His international experience in Japan and Korea highlighted his adaptability and willingness to embrace new challenges in different baseball cultures.

Throughout his career, Petagine was known for his left-handed power hitting and his ability to get on base.