Mike Hargrove's journey in Major League Baseball began when he was drafted by the Texas Rangers in the 25th round of the 1972 MLB Draft. Known for his meticulous routine at the plate, which earned him the nickname "The Human Rain Delay," Hargrove made his MLB debut with the Rangers in 1974. His rookie season was impressive, as he batted .323 and earned the American League Rookie of the Year award.

Hargrove played as a first baseman and outfielder during his career. After his initial years with the Rangers, he was traded to the San Diego Padres in 1978. His time with the Padres was brief, and he was soon traded to the Cleveland Indians in 1979. It was with the Indians that Hargrove spent the majority of his playing career, becoming a fan favorite for his consistent performance and disciplined approach at the plate. He played with the Indians until 1985, finishing his playing career with the team.

Throughout his playing career, Hargrove was known for his ability to get on base. He had a career batting average of .290 and an on-base percentage of .396, demonstrating his skill in drawing walks and making contact. His patient approach at the plate was a hallmark of his playing style, frustrating pitchers and earning him respect across the league.

After retiring as a player, Hargrove transitioned into coaching and management. He began his managerial career with the Cleveland Indians in 1991. Under his leadership, the Indians became one of the dominant teams in the American League during the mid-1990s. Hargrove guided the team to five consecutive AL Central Division titles from 1995 to 1999. The Indians reached the World Series twice during his tenure, in 1995 and 1997, though they fell short of winning the championship both times.

Hargrove's managerial style was characterized by his calm demeanor and ability to handle a diverse roster of talent. He was known for fostering a strong team spirit and getting the best out of his players. After leaving the Indians in 1999, Hargrove went on to manage the Baltimore Orioles from 2000 to 2003. His time with the Orioles was less successful, as the team struggled to find its footing in a competitive division.

In 2005, Hargrove took on the role of manager for the Seattle Mariners. His tenure with the Mariners was marked by a surprising decision to resign midway through the 2007 season, citing personal reasons and a lack of passion for the game. This unexpected move came as the Mariners were performing well, adding an intriguing chapter to his managerial career.