In 1966, Santiago's career took a significant turn when he was traded to the Boston Red Sox. This move proved to be a defining moment, as he became an integral part of the Red Sox pitching staff. Santiago's tenure with Boston coincided with one of the most memorable seasons in the franchise's history. The 1967 season, often referred to as the "Impossible Dream," saw the Red Sox capture the American League pennant, and Santiago played a crucial role in this achievement.
During the 1967 season, Santiago's performance was instrumental in the Red Sox's success. He posted a solid record as a starting pitcher and was known for his ability to deliver in high-pressure situations. His efforts were particularly evident during the World Series against the St. Louis Cardinals. Santiago started Game 1 of the series and pitched admirably, even hitting a home run, which was a rare feat for a pitcher. Although the Red Sox ultimately fell to the Cardinals in seven games, Santiago's contributions were widely recognized.
Santiago continued to pitch for the Red Sox through the late 1960s. His repertoire included a mix of fastballs and off-speed pitches, which kept hitters off balance. Despite facing challenges such as injuries, he remained a reliable option for the Red Sox rotation. His ability to adapt and compete at a high level was evident throughout his career.
After his time with the Red Sox, Santiago's major league career came to a close. However, his impact on the teams he played for, particularly the 1967 Red Sox, left a lasting impression on fans and teammates alike. Santiago's career in baseball extended beyond his playing days, as he remained involved in the sport in various capacities.
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