Jesus Colome, a right-handed relief pitcher, made his presence known in Major League Baseball with a fastball that often reached the upper 90s, occasionally touching 100 mph. Born on December 23, 1977, in the Dominican Republic, Colome's journey to the major leagues began when he was signed by the Oakland Athletics as an amateur free agent in 1996. However, it was with the Tampa Bay Devil Rays that he would first step onto a major league mound.

Colome debuted with the Devil Rays on June 21, 2001. During his time with Tampa Bay, he became known for his powerful arm and ability to strike out batters, though control issues sometimes plagued his performances. Over the course of his tenure with the Devil Rays, which lasted until 2006, Colome appeared in 129 games, primarily as a reliever. His tenure with the team was marked by moments of brilliance interspersed with challenges, as he worked to harness his raw talent into consistent performance.

In 2006, Colome was released by the Devil Rays and subsequently signed by the Washington Nationals. His stint with the Nationals provided him with a fresh start, and he pitched for them from 2006 to 2008. During this period, Colome appeared in 129 games, maintaining a solid presence in the bullpen. His time with the Nationals was highlighted by a career-best season in 2007, where he posted a 3.82 ERA over 61 appearances, showcasing his ability to be a reliable option out of the bullpen.

After his time with the Nationals, Colome signed with the Milwaukee Brewers in 2009. However, his tenure with the Brewers was brief, as he only appeared in 16 games before being released. Later that year, he was picked up by the Seattle Mariners, where he finished the season. His time with the Mariners was short-lived, and he became a free agent at the end of the season.

In 2010, Colome signed a minor league contract with the Texas Rangers, though he did not make an appearance for the major league team. This marked the end of his major league career, as he continued to play in various minor league and independent league teams in the following years.

Throughout his career, Jesus Colome was known for his powerful fastball and his role as a relief pitcher.