Jack Fisher, known for his role as a pitcher in Major League Baseball, embarked on his professional career when he signed with the Baltimore Orioles. Born on March 4, 1939, in Frostburg, Maryland, Fisher quickly rose through the ranks, making his MLB debut with the Orioles in 1959. His early years with Baltimore were marked by a learning curve typical of young pitchers, but he soon established himself as a reliable arm in the rotation.

Fisher's tenure with the Orioles lasted until 1962, during which he gained valuable experience and honed his skills on the mound. In 1962, he was traded to the San Francisco Giants, where he spent a brief period before being traded again, this time to the New York Mets. It was with the Mets that Fisher became more widely recognized, as he was part of the team during its formative years.

Pitching for the Mets from 1964 to 1967, Fisher was often called upon to face some of the toughest lineups in the league. Despite the Mets' struggles during this era, Fisher's perseverance and ability to handle a heavy workload were evident. He led the league in losses in 1965 and 1967, a testament to the challenges faced by the Mets during those seasons, but also indicative of his role as a workhorse pitcher who was frequently relied upon to start games.

One of the most memorable moments of Fisher's career came on September 11, 1964, when he surrendered a home run to Willie Mays, marking Mays' 400th career homer. Such instances highlighted Fisher's place in baseball history, often finding himself on the mound during significant moments.

After his stint with the Mets, Fisher was traded to the Chicago White Sox in 1968. His time with the White Sox was relatively short, but he continued to contribute as a starting pitcher. In 1969, Fisher moved to the Cincinnati Reds, where he concluded his major league career. Over the course of his career, Fisher compiled a win-loss record of 86-139, with an earned run average (ERA) of 4.06 and 1,017 strikeouts.