Gavin Floyd, a right-handed pitcher, began his Major League Baseball career with the Philadelphia Phillies. Drafted fourth overall in the 2001 MLB Draft, Floyd was highly regarded for his pitching potential. He made his MLB debut with the Phillies on September 3, 2004, against the New York Mets. During his time with Philadelphia, Floyd showed flashes of his talent but struggled with consistency, which led to a mixed performance over his initial seasons.

In December 2006, Floyd was traded to the Chicago White Sox along with Gio González in exchange for Freddy García. This move marked a turning point in his career. With the White Sox, Floyd found more stability and success. The 2008 season was particularly noteworthy for him. He posted a 17-8 record with a 3.84 ERA, helping the White Sox reach the postseason. That year, Floyd also came close to pitching a no-hitter on two occasions, showcasing his ability to dominate opposing lineups.

Floyd continued to be a reliable starter for the White Sox over the next few seasons. He consistently delivered solid performances, contributing to the team's rotation. However, injuries began to affect his career. In 2013, Floyd underwent Tommy John surgery after tearing the ulnar collateral ligament in his right elbow. This surgery sidelined him for the remainder of the season and impacted his future performance.

After recovering, Floyd signed with the Atlanta Braves for the 2014 season. He made nine starts for the Braves, posting a 2.65 ERA, before suffering another setback with a fractured elbow, which ended his season prematurely. Despite these challenges, Floyd continued to pursue his career in the majors.

In 2015, Floyd joined the Cleveland Indians, where he worked primarily out of the bullpen. His time with the Indians was short-lived, as he was again plagued by injuries. The following year, Floyd signed with the Toronto Blue Jays. During the 2016 season, he appeared in 28 games, mostly as a reliever, before another injury cut his season short.

Throughout his career, Floyd was known for his curveball, which was considered one of his best pitches. His ability to mix pitches and keep hitters off balance was a key aspect of his game. Despite the setbacks and injuries, Floyd's career in Major League Baseball spanned over a decade, during which he demonstrated resilience and adaptability.