Daniel Descalso, a professional baseball infielder, began his Major League Baseball (MLB) career with the St. Louis Cardinals. Drafted by the Cardinals in the third round of the 2007 MLB Draft, Descalso made his MLB debut on September 18, 2010. Known for his defensive versatility, he played primarily as a second baseman but also covered shortstop and third base when needed.

During his time with the Cardinals, Descalso became known for his clutch performances in the postseason. He was part of the Cardinals' roster that won the World Series in 2011, contributing to the team's success with timely hitting and reliable defense. In the 2011 National League Division Series against the Philadelphia Phillies, Descalso's performance helped the Cardinals advance, and he continued to play a role throughout the postseason.

Descalso remained with the Cardinals through the 2014 season. Over these years, he provided depth to the infield and was often called upon in late-game situations. His ability to play multiple positions made him a valuable asset to the team, and he was appreciated for his steady presence on the field.

In December 2014, Descalso signed a two-year contract with the Colorado Rockies. With the Rockies, he continued to demonstrate his infield versatility and contributed as a utility player. His time in Colorado saw him taking on more of a leadership role, guiding younger players and providing experience to the roster.

After his stint with the Rockies, Descalso joined the Arizona Diamondbacks in 2017. His tenure with the Diamondbacks was marked by a career-high in home runs during the 2018 season, showcasing his ability to contribute offensively. Descalso's performance helped the Diamondbacks reach the postseason in 2017, where they advanced to the National League Division Series.

In December 2018, Descalso signed with the Chicago Cubs. His role with the Cubs was similar to his previous teams, where he provided infield depth and experience. However, his time with the Cubs was marred by injuries, which limited his playing time and effectiveness on the field.

Throughout his career, Descalso was known for his professionalism and team-first mentality. His ability to adapt to different roles and positions made him a valuable player for every team he joined. While not always in the spotlight, Descalso's contributions were appreciated by teammates and coaches alike.