Cal Eldred's journey through Major League Baseball began when he was drafted by the Milwaukee Brewers in the first round of the 1989 MLB Draft. A right-handed pitcher, Eldred made his major league debut with the Brewers on September 24, 1991. His early years with the team were marked by promise, as he quickly established himself as a reliable starter.

In 1992, Eldred's first full season, he posted an impressive 11-2 record with a 1.79 ERA in 14 starts, showcasing his potential as a top-tier pitcher. The following year, he continued to perform well, leading the American League in innings pitched with 258 and recording 16 wins. His ability to consistently deliver quality starts made him a valuable asset to the Brewers' rotation.

Eldred's tenure with the Brewers, however, was not without challenges. Injuries began to take a toll on his performance and availability. Despite these setbacks, he remained a fixture in Milwaukee's pitching staff throughout the mid-1990s. His perseverance through these difficulties demonstrated his commitment to the game and his team.

In 1999, Eldred was traded to the Chicago White Sox. His time in Chicago was marred by further injuries, limiting his effectiveness on the mound. Nevertheless, he managed to contribute to the team when healthy, providing veteran leadership and experience to a young pitching staff.

After his stint with the White Sox, Eldred signed with the St. Louis Cardinals in 2003. Transitioning to a relief role, he found a new niche in the Cardinals' bullpen. This move allowed him to extend his career and continue competing at the major league level. During his time with the Cardinals, Eldred was part of the team that reached the World Series in 2004, although they ultimately fell to the Boston Red Sox.

Eldred's career concluded after the 2005 season, marking the end of a 14-year journey in Major League Baseball. Over the course of his career, he accumulated a record of 86 wins and 74 losses, with an ERA of 4.42. His ability to adapt to different roles and overcome injuries underscored his determination and love for the sport.