Andy Pettitte, a left-handed pitcher, became a household name in Major League Baseball, primarily with the New York Yankees and the Houston Astros. Born on June 15, 1972, in Baton Rouge, Louisiana, Pettitte grew up in Deer Park, Texas, where he honed his skills on the baseball diamond. His journey to the major leagues began when the Yankees selected him in the 22nd round of the 1990 MLB Draft.

Pettitte made his MLB debut with the Yankees on April 29, 1995. Quickly establishing himself as a reliable starter, he finished his rookie season with a 12-9 record and a 4.17 ERA. The following year, he improved significantly, posting a 21-8 record and a 3.87 ERA, which earned him a second-place finish in the American League Cy Young Award voting.

Throughout his career, Pettitte was known for his consistency and ability to perform under pressure, particularly in the postseason. He played a crucial role in the Yankees' success during the late 1990s and early 2000s, helping the team secure World Series titles in 1996, 1998, 1999, and 2000. His postseason record is one of the most impressive in MLB history, with 19 wins, the most by any pitcher in playoff history.

In 2004, Pettitte signed with the Houston Astros, where he continued to excel. During his three seasons with the Astros, he helped lead the team to its first World Series appearance in 2005. Pettitte returned to the Yankees in 2007, where he continued to be a vital part of their pitching rotation. He added another World Series title to his resume in 2009 when the Yankees defeated the Philadelphia Phillies.

Pettitte's pitching style was characterized by his strong command and ability to mix pitches effectively. His arsenal included a fastball, cutter, curveball, and changeup, which he used to keep hitters off balance. Over his career, he accumulated 256 wins, 2,448 strikeouts, and a 3.85 ERA.

Off the field, Pettitte was known for his calm demeanor and leadership qualities. He was respected by teammates and opponents alike for his professionalism and sportsmanship. In 2007, Pettitte's name was mentioned in the Mitchell Report, which investigated the use of performance-enhancing drugs in baseball. He admitted to using human growth hormone (HGH) briefly in 2002 to recover from an elbow injury, an admission that he later expressed regret over.

After initially retiring in 2011, Pettitte returned to the Yankees in 2012 for two more seasons before retiring for good in 2013. His number 46 was retired by the Yankees in 2015, and he was honored with a plaque in Monument Park, recognizing his contributions to the team's storied history.